D37N (p.Asp37Asn) variant of SERPINE1 (P05121)
D37N (p.Asp37Asn) in SERPINE1 (P05121) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
D37N (p.Asp37Asn) variant details
- p.Asp37Asn
- ExAC rs771977842
- TOPMed rs771977842
- gnomAD rs771977842
- Missense
- Variant Prioritization Score for Impact Estimate 0.337
- REVEL 0.24
- CADD 22.40
- PolyPhen-2 0.03
- SIFT 0.22
- Most common in the Middle Eastern population (allele frequency 0.00017)
- Structural context available