D37G (p.Asp37Gly) variant of SERPINE1 (P05121)
D37G (p.Asp37Gly) in SERPINE1 (P05121) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data, published literature, and structural context.
D37G (p.Asp37Gly) variant details
- p.Asp37Gly
- gnomAD 7-101128503-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.608
- REVEL 0.64
- CADD 29.10
- PolyPhen-2 0.66
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available