A35D (p.Ala35Asp) variant of SERPINE1 (P05121)
A35D (p.Ala35Asp) in SERPINE1 (P05121) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, published literature, and structural context.
A35D (p.Ala35Asp) variant details
- p.Ala35Asp
- gnomAD 7-101128497-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.263
- REVEL 0.20
- CADD 23.40
- PolyPhen-2 0.89
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available