A15V (p.Ala15Val) variant of SERPINE1 (P05121)
A15V (p.Ala15Val) in SERPINE1 (P05121) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data, published literature, and structural context.
A15V (p.Ala15Val) variant details
- p.Ala15Val
- gnomAD 7-101128437-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.339
- REVEL 0.29
- CADD 16.00
- PolyPhen-2 0.00
- SIFT 0.34
- Most common in the Non-Finnish European population (allele frequency 6.3e-06)
- Structural context available
- Literature evidence available