V4G (p.Val4Gly) variant of SDHB (P21912)
V4G (p.Val4Gly) in SDHB (P21912) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
V4G (p.Val4Gly) variant details
- p.Val4Gly
- ExAC rs776656866
- Missense
- Variant Prioritization Score for Impact Estimate 0.399
- REVEL 0.44
- AlphaMissense 0.07
- MetaLR 0.82
- MetaSVM 0.11
- CADD 22.80
- PolyPhen-2 0.01
- Most common in the Finnish in Finland (FIN) population (allele frequency 3.8e-05)
- Structural context available