S4S (p.Ser4Ser) variant of SDHAF2 (Q9NX18)
S4S (p.Ser4Ser) in SDHAF2 (Q9NX18) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data, published literature, and structural context.
S4S (p.Ser4Ser) variant details
- p.Ser4Ser
- rs2135436188
- gnomAD 11-61430158-T-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.113
- CADD 4.50
- Most common in the African/African-American population (allele frequency 0.00041)
- Structural context available
- Literature evidence available