R15S (p.Arg15Ser) variant of SCN5A (Nav1.5)
R15S (p.Arg15Ser) in SCN5A (Nav1.5) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes structural context.
R15S (p.Arg15Ser) variant details
- p.Arg15Ser
- NCI-TCGA Cosmic COSV6006
- cosmic curated COSV60067
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.223
- ESM-1b 0.00
- AlphaMissense 0.54
- UniProt: Variant assessed as somatic; moderate impact.
- Structural context available