P155T (p.Pro155Thr) variant of SCN5A (Nav1.5)
P155T (p.Pro155Thr) in SCN5A (Nav1.5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
P155T (p.Pro155Thr) variant details
- p.Pro155Thr
- cosmic curated COSV61115
- Missense
- Variant Prioritization Score for Impact Estimate 0.383
- REVEL 0.25
- ESM-1b 0.78
- AlphaMissense 0.08
- MetaLR 0.70
- MetaSVM -0.13
- CADD 21.70
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available