F1447S (p.Phe1447Ser) variant of SCN4A (Nav1.4)

F1447S (p.Phe1447Ser) in SCN4A (Nav1.4) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as likely pathogenic in the context of Congenital myopathy 22B, severe fetal. The record also includes structural context.

F1447S (p.Phe1447Ser) variant details