G10V (p.Gly10Val) variant of SCN2A (Q99250)
G10V (p.Gly10Val) in SCN2A (Q99250) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.94 / 1. The record also includes structural context.
G10V (p.Gly10Val) variant details
- p.Gly10Val
- NCI-TCGA Cosmic COSV5184
- NCI-TCGA Cosmic COSV9933
- cosmic curated COSV99330
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.942
- ESM-1b 1.00
- AlphaMissense 0.87
- UniProt: Variant assessed as somatic; moderate impact.
- Structural context available