M93T (p.Met93Thr) variant of SCN10A (Nav1.8)
M93T (p.Met93Thr) in SCN10A (Nav1.8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.63 / 1. The record also includes population frequency data and structural context.
M93T (p.Met93Thr) variant details
- p.Met93Thr
- gnomAD rs1286871655
- Missense
- Variant Prioritization Score for Impact Estimate 0.634
- REVEL 0.60
- MetaLR 0.80
- MetaSVM 0.98
- CADD 23.50
- PolyPhen-2 0.07
- SIFT 0.00
- Most common in the HGDP:BRAHUI population (allele frequency 0.022)
- Structural context available