L74P (p.Leu74Pro) variant of SCN10A (Nav1.8)
L74P (p.Leu74Pro) in SCN10A (Nav1.8) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as uncertain significance in the context of Cardiovascular phenotype. The record also includes structural context.
L74P (p.Leu74Pro) variant details
- p.Leu74Pro
- rs2064315891
- ClinGen CA352162642
- ClinVar RCV002428068
- TOPMed rs2064315891
- Uncertain significance
- Cardiovascular phenotype
- Missense
- ClinVar: Uncertain significance (Cardiovascular phenotype)
- EBI: Variant of uncertain significance
- UniProt: Uncertain significance
- Structural context available