K40T (p.Lys40Thr) variant of SCN10A (Nav1.8)
K40T (p.Lys40Thr) in SCN10A (Nav1.8) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The record also includes variant effect predictions and structural context.
K40T (p.Lys40Thr) variant details
- p.Lys40Thr
- NCI-TCGA Cosmic COSV1014
- cosmic curated COSV10147
- Variant assessed as somatic; moderate impact.
- Missense
- MetaLR 0.73
- MetaSVM 0.04
- SIFT 0.11
- UniProt: Variant assessed as somatic; moderate impact.
- Structural context available