E25K (p.Glu25Lys) variant of SCN10A (Nav1.8)
E25K (p.Glu25Lys) in SCN10A (Nav1.8) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as uncertain significance in the context of Cardiovascular phenotype. The record also includes structural context.
E25K (p.Glu25Lys) variant details
- p.Glu25Lys
- rs2470901875
- ClinGen CA352163300
- ClinVar RCV002380521
- NCI-TCGA Cosmic COSV7186
- Uncertain significance
- Cardiovascular phenotype
- Missense
- ClinVar: Uncertain significance (Cardiovascular phenotype)
- EBI: Variant of uncertain significance
- UniProt: Uncertain significance
- Structural context available