R4W (p.Arg4Trp) variant of SATB2 (DNA-binding protein SATB2)
R4W (p.Arg4Trp) in SATB2 (DNA-binding protein SATB2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
R4W (p.Arg4Trp) variant details
- p.Arg4Trp
- cosmic curated COSV53489
- Missense
- Variant Prioritization Score for Impact Estimate 0.507
- REVEL 0.24
- ESM-1b 1.00
- AlphaMissense 0.25
- CADD 32.00
- PolyPhen-2 0.64
- SIFT 0.04
- Most common in the Finnish in Finland (FIN) population (allele frequency 2.8e-05)
- Structural context available