P28S (p.Pro28Ser) variant of SATB2 (DNA-binding protein SATB2)
P28S (p.Pro28Ser) in SATB2 (DNA-binding protein SATB2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
P28S (p.Pro28Ser) variant details
- p.Pro28Ser
- cosmic curated COSV53480
- Missense
- Variant Prioritization Score for Impact Estimate 0.347
- REVEL 0.17
- ESM-1b 0.24
- AlphaMissense 0.10
- CADD 24.20
- PolyPhen-2 0.09
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 9.3e-07)
- Structural context available