M59V (p.Met59Val) variant of SATB2 (DNA-binding protein SATB2)
M59V (p.Met59Val) in SATB2 (DNA-binding protein SATB2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data and structural context.
M59V (p.Met59Val) variant details
- p.Met59Val
- gnomAD rs1478238325
- Missense
- Variant Prioritization Score for Impact Estimate 0.483
- REVEL 0.30
- ESM-1b 1.00
- AlphaMissense 0.48
- CADD 23.40
- PolyPhen-2 0.09
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available