L102P (p.Leu102Pro) variant of SATB2 (DNA-binding protein SATB2)
L102P (p.Leu102Pro) in SATB2 (DNA-binding protein SATB2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.68 / 1. The record also includes population frequency data and structural context.
L102P (p.Leu102Pro) variant details
- p.Leu102Pro
- gnomAD rs1691560087
- Missense
- Variant Prioritization Score for Impact Estimate 0.678
- REVEL 0.60
- ESM-1b 1.00
- AlphaMissense 1.00
- CADD 29.80
- PolyPhen-2 0.96
- SIFT 0.00
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available