D133Y (p.Asp133Tyr) variant of SATB2 (DNA-binding protein SATB2)
D133Y (p.Asp133Tyr) in SATB2 (DNA-binding protein SATB2) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.94 / 1. The record also includes structural context.
D133Y (p.Asp133Tyr) variant details
- p.Asp133Tyr
- NCI-TCGA Cosmic COSV5348
- cosmic curated COSV53489
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.944
- ESM-1b 1.00
- AlphaMissense 0.88
- UniProt: Variant assessed as somatic; moderate impact.
- Structural context available