C64T (p.Cys64Thr) variant of SATB2 (DNA-binding protein SATB2)
C64T (p.Cys64Thr) in SATB2 (DNA-binding protein SATB2) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
C64T (p.Cys64Thr) variant details
- p.Cys64Thr
- rs1367686940
- gnomAD rs1367686940
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.402
- AlphaMissense 0.13
- MetaLR 0.40
- MetaSVM -0.26
- PolyPhen-2 0.30
- SIFT 0.00
- EVE 0.15
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available