C25Y (p.Cys25Tyr) variant of RYR3 (Ryanodine receptor 3)
C25Y (p.Cys25Tyr) in RYR3 (Ryanodine receptor 3) is a missense change. The record also includes variant effect predictions and population frequency data.
C25Y (p.Cys25Tyr) variant details
- p.Cys25Tyr
- gnomAD rs1462227309
- Missense
- MetaLR 0.97
- MetaSVM 1.10
- CADD 27.10
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)