W72S (p.Trp72Ser) variant of RRAD (GTP-binding protein RAD)
W72S (p.Trp72Ser) in RRAD (GTP-binding protein RAD) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
W72S (p.Trp72Ser) variant details
- p.Trp72Ser
- ExAC rs746198967
- gnomAD rs746198967
- Missense
- Variant Prioritization Score for Impact Estimate 0.385
- REVEL 0.22
- ESM-1b 0.00
- AlphaMissense 0.11
- CADD 22.80
- PolyPhen-2 0.20
- SIFT 0.08
- Most common in the South Asian population (allele frequency 1.3e-05)
- Structural context available