W29C (p.Trp29Cys) variant of RRAD (GTP-binding protein RAD)
W29C (p.Trp29Cys) in RRAD (GTP-binding protein RAD) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
W29C (p.Trp29Cys) variant details
- p.Trp29Cys
- TOPMed rs1962978106
- Missense
- Variant Prioritization Score for Impact Estimate 0.342
- REVEL 0.12
- ESM-1b 0.00
- AlphaMissense 0.34
- CADD 25.20
- PolyPhen-2 0.24
- SIFT 0.01
- Most common in the South Asian population (allele frequency 4.4e-05)
- Structural context available