T63R (p.Thr63Arg) variant of RRAD (GTP-binding protein RAD)
T63R (p.Thr63Arg) in RRAD (GTP-binding protein RAD) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
T63R (p.Thr63Arg) variant details
- p.Thr63Arg
- TOPMed rs1313000729
- gnomAD rs1313000729
- Missense
- Variant Prioritization Score for Impact Estimate 0.187
- REVEL 0.09
- ESM-1b 0.00
- AlphaMissense 0.08
- CADD 13.60
- PolyPhen-2 0.05
- SIFT 0.21
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available