R45S (p.Arg45Ser) variant of RRAD (GTP-binding protein RAD)
R45S (p.Arg45Ser) in RRAD (GTP-binding protein RAD) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
R45S (p.Arg45Ser) variant details
- p.Arg45Ser
- gnomAD rs1962976685
- Missense
- Variant Prioritization Score for Impact Estimate 0.358
- REVEL 0.23
- ESM-1b 0.00
- AlphaMissense 0.32
- CADD 23.80
- PolyPhen-2 0.26
- SIFT 0.08
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available