R38C (p.Arg38Cys) variant of RRAD (GTP-binding protein RAD)
R38C (p.Arg38Cys) in RRAD (GTP-binding protein RAD) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
R38C (p.Arg38Cys) variant details
- p.Arg38Cys
- cosmic curated COSV10962
- TOPMed rs1267935196
- gnomAD rs1267935196
- Missense
- Variant Prioritization Score for Impact Estimate 0.449
- REVEL 0.29
- ESM-1b 1.00
- AlphaMissense 0.43
- CADD 26.10
- PolyPhen-2 0.82
- SIFT 0.13
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available