R24W (p.Arg24Trp) variant of RRAD (GTP-binding protein RAD)
R24W (p.Arg24Trp) in RRAD (GTP-binding protein RAD) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.56 / 1. The record also includes population frequency data and structural context.
R24W (p.Arg24Trp) variant details
- p.Arg24Trp
- TOPMed rs943979474
- gnomAD rs943979474
- Missense
- Variant Prioritization Score for Impact Estimate 0.56
- REVEL 0.38
- ESM-1b 1.00
- AlphaMissense 0.67
- CADD 31.00
- PolyPhen-2 0.49
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available