R23C (p.Arg23Cys) variant of RRAD (GTP-binding protein RAD)
R23C (p.Arg23Cys) in RRAD (GTP-binding protein RAD) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
R23C (p.Arg23Cys) variant details
- p.Arg23Cys
- Ensembl rs1596995072
- Missense
- Variant Prioritization Score for Impact Estimate 0.515
- REVEL 0.26
- ESM-1b 1.00
- AlphaMissense 0.64
- CADD 27.50
- PolyPhen-2 0.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 3.3e-06)
- Structural context available