R22H (p.Arg22His) variant of RRAD (GTP-binding protein RAD)
R22H (p.Arg22His) in RRAD (GTP-binding protein RAD) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
R22H (p.Arg22His) variant details
- p.Arg22His
- gnomAD rs1962978874
- Missense
- Variant Prioritization Score for Impact Estimate 0.335
- REVEL 0.06
- ESM-1b 0.67
- AlphaMissense 0.20
- CADD 24.90
- PolyPhen-2 0.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available