R20S (p.Arg20Ser) variant of RRAD (GTP-binding protein RAD)
R20S (p.Arg20Ser) in RRAD (GTP-binding protein RAD) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
R20S (p.Arg20Ser) variant details
- p.Arg20Ser
- TOPMed rs1049543710
- Missense
- Variant Prioritization Score for Impact Estimate 0.294
- REVEL 0.16
- ESM-1b 0.00
- AlphaMissense 0.21
- CADD 23.40
- PolyPhen-2 0.03
- SIFT 0.12
- Most common in the Non-Finnish European population (allele frequency 1.9e-05)
- Structural context available