P28L (p.Pro28Leu) variant of RRAD (GTP-binding protein RAD)
P28L (p.Pro28Leu) in RRAD (GTP-binding protein RAD) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
P28L (p.Pro28Leu) variant details
- p.Pro28Leu
- TOPMed rs1962978145
- Missense
- Variant Prioritization Score for Impact Estimate 0.331
- REVEL 0.18
- ESM-1b 0.00
- AlphaMissense 0.31
- CADD 24.60
- PolyPhen-2 0.15
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.1e-06)
- Structural context available