L80P (p.Leu80Pro) variant of RRAD (GTP-binding protein RAD)
L80P (p.Leu80Pro) in RRAD (GTP-binding protein RAD) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
L80P (p.Leu80Pro) variant details
- p.Leu80Pro
- ExAC rs776429078
- TOPMed rs776429078
- gnomAD rs776429078
- Missense
- Variant Prioritization Score for Impact Estimate 0.278
- REVEL 0.10
- ESM-1b 0.00
- AlphaMissense 0.08
- CADD 23.10
- PolyPhen-2 0.28
- SIFT 0.37
- Most common in the Non-Finnish European population (allele frequency 3.2e-05)
- Structural context available