L35Q (p.Leu35Gln) variant of RRAD (GTP-binding protein RAD)
L35Q (p.Leu35Gln) in RRAD (GTP-binding protein RAD) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
L35Q (p.Leu35Gln) variant details
- p.Leu35Gln
- TOPMed rs1962977575
- Missense
- Variant Prioritization Score for Impact Estimate 0.361
- REVEL 0.26
- ESM-1b 0.00
- AlphaMissense 0.11
- CADD 23.10
- PolyPhen-2 0.29
- SIFT 0.72
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available