L107P (p.Leu107Pro) variant of RRAD (GTP-binding protein RAD)
L107P (p.Leu107Pro) in RRAD (GTP-binding protein RAD) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.82 / 1. The record also includes population frequency data and structural context.
L107P (p.Leu107Pro) variant details
- p.Leu107Pro
- TOPMed rs1962970956
- Missense
- Variant Prioritization Score for Impact Estimate 0.816
- REVEL 0.89
- ESM-1b 1.00
- AlphaMissense 1.00
- CADD 28.20
- PolyPhen-2 0.92
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available