I110L (p.Ile110Leu) variant of RRAD (GTP-binding protein RAD)
I110L (p.Ile110Leu) in RRAD (GTP-binding protein RAD) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
I110L (p.Ile110Leu) variant details
- p.Ile110Leu
- ExAC rs764130794
- TOPMed rs764130794
- gnomAD rs764130794
- Missense
- Variant Prioritization Score for Impact Estimate 0.426
- REVEL 0.26
- ESM-1b 0.64
- AlphaMissense 0.29
- CADD 21.80
- PolyPhen-2 0.08
- SIFT 0.46
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available