G17C (p.Gly17Cys) variant of RRAD (GTP-binding protein RAD)
G17C (p.Gly17Cys) in RRAD (GTP-binding protein RAD) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
G17C (p.Gly17Cys) variant details
- p.Gly17Cys
- TOPMed rs1400562666
- gnomAD rs1400562666
- Missense
- Variant Prioritization Score for Impact Estimate 0.314
- REVEL 0.19
- ESM-1b 0.83
- AlphaMissense 0.10
- CADD 22.50
- PolyPhen-2 0.17
- SIFT 0.06
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available