E77K (p.Glu77Lys) variant of RRAD (GTP-binding protein RAD)
E77K (p.Glu77Lys) in RRAD (GTP-binding protein RAD) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
E77K (p.Glu77Lys) variant details
- p.Glu77Lys
- Ensembl rs997985313
- Missense
- Variant Prioritization Score for Impact Estimate 0.301
- REVEL 0.09
- ESM-1b 1.00
- AlphaMissense 0.16
- CADD 21.20
- PolyPhen-2 0.01
- SIFT 0.21
- Most common in the East Asian population (allele frequency 5.6e-05)
- Structural context available