E21K (p.Glu21Lys) variant of RRAD (GTP-binding protein RAD)
E21K (p.Glu21Lys) in RRAD (GTP-binding protein RAD) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
E21K (p.Glu21Lys) variant details
- p.Glu21Lys
- gnomAD rs1218895180
- Missense
- Variant Prioritization Score for Impact Estimate 0.251
- REVEL 0.07
- ESM-1b 0.00
- AlphaMissense 0.32
- CADD 23.60
- PolyPhen-2 0.00
- SIFT 0.19
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available