D75G (p.Asp75Gly) variant of RRAD (GTP-binding protein RAD)
D75G (p.Asp75Gly) in RRAD (GTP-binding protein RAD) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
D75G (p.Asp75Gly) variant details
- p.Asp75Gly
- TOPMed rs1049596379
- gnomAD rs1049596379
- Missense
- Variant Prioritization Score for Impact Estimate 0.254
- REVEL 0.13
- ESM-1b 0.00
- AlphaMissense 0.07
- CADD 17.80
- PolyPhen-2 0.00
- SIFT 0.49
- Most common in the African/African-American population (allele frequency 0.00015)
- Structural context available