D46Y (p.Asp46Tyr) variant of RRAD (GTP-binding protein RAD)
D46Y (p.Asp46Tyr) in RRAD (GTP-binding protein RAD) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
D46Y (p.Asp46Tyr) variant details
- p.Asp46Tyr
- TOPMed rs980269575
- gnomAD rs980269575
- Missense
- Variant Prioritization Score for Impact Estimate 0.394
- REVEL 0.20
- ESM-1b 0.00
- AlphaMissense 0.23
- CADD 29.10
- PolyPhen-2 0.89
- SIFT 0.05
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available