D46G (p.Asp46Gly) variant of RRAD (GTP-binding protein RAD)
D46G (p.Asp46Gly) in RRAD (GTP-binding protein RAD) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
D46G (p.Asp46Gly) variant details
- p.Asp46Gly
- gnomAD rs1962976523
- Missense
- Variant Prioritization Score for Impact Estimate 0.311
- REVEL 0.16
- ESM-1b 0.00
- AlphaMissense 0.19
- CADD 23.30
- PolyPhen-2 0.32
- SIFT 0.64
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available