A61P (p.Ala61Pro) variant of RRAD (GTP-binding protein RAD)
A61P (p.Ala61Pro) in RRAD (GTP-binding protein RAD) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
A61P (p.Ala61Pro) variant details
- p.Ala61Pro
- ExAC rs761881979
- TOPMed rs761881979
- gnomAD rs761881979
- Missense
- Variant Prioritization Score for Impact Estimate 0.106
- REVEL 0.06
- ESM-1b 0.00
- AlphaMissense 0.06
- CADD 11.70
- PolyPhen-2 0.00
- SIFT 0.31
- Most common in the HGDP:BURUSHO population (allele frequency 0.021)
- Structural context available