A108V (p.Ala108Val) variant of RRAD (GTP-binding protein RAD)
A108V (p.Ala108Val) in RRAD (GTP-binding protein RAD) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.68 / 1. The record also includes population frequency data and structural context.
A108V (p.Ala108Val) variant details
- p.Ala108Val
- ExAC rs767737687
- TOPMed rs767737687
- gnomAD rs767737687
- Missense
- Variant Prioritization Score for Impact Estimate 0.681
- REVEL 0.56
- ESM-1b 1.00
- AlphaMissense 0.59
- CADD 25.50
- PolyPhen-2 1.00
- SIFT 0.10
- Most common in the East Asian population (allele frequency 2.6e-05)
- Structural context available