V64L (p.Val64Leu) variant of RNF215 (RING finger protein 215)
V64L (p.Val64Leu) in RNF215 (RING finger protein 215) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
V64L (p.Val64Leu) variant details
- p.Val64Leu
- gnomAD rs1382667878
- Missense
- Variant Prioritization Score for Impact Estimate 0.28
- REVEL 0.07
- ESM-1b 0.00
- AlphaMissense 0.39
- MetaLR 0.03
- MetaSVM -1.00
- CADD 22.10
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available