V62M (p.Val62Met) variant of RNF215 (RING finger protein 215)
V62M (p.Val62Met) in RNF215 (RING finger protein 215) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
V62M (p.Val62Met) variant details
- p.Val62Met
- TOPMed rs1309305538
- gnomAD rs1309305538
- Missense
- Variant Prioritization Score for Impact Estimate 0.441
- REVEL 0.11
- ESM-1b 1.00
- AlphaMissense 0.72
- CADD 25.60
- PolyPhen-2 0.97
- SIFT 0.01
- Most common in the HGDP:BANTUKENYA population (allele frequency 0.2)
- Structural context available