R6S (p.Arg6Ser) variant of RNF215 (RING finger protein 215)
R6S (p.Arg6Ser) in RNF215 (RING finger protein 215) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
R6S (p.Arg6Ser) variant details
- p.Arg6Ser
- gnomAD rs1173236038
- Missense
- Variant Prioritization Score for Impact Estimate 0.209
- REVEL 0.08
- ESM-1b 0.00
- AlphaMissense 0.27
- CADD 19.10
- PolyPhen-2 0.01
- SIFT 0.09
- Most common in the REMAINING population (allele frequency 3.3e-05)
- Structural context available