R61S (p.Arg61Ser) variant of RNF215 (RING finger protein 215)
R61S (p.Arg61Ser) in RNF215 (RING finger protein 215) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data, published literature, and structural context.
R61S (p.Arg61Ser) variant details
- p.Arg61Ser
- rs1933206256
- gnomAD 22-30374612-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.43
- ESM-1b 0.00
- AlphaMissense 0.30
- CADD 4.88
- SIFT 0.34
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available
- Literature evidence available