R58C (p.Arg58Cys) variant of RNF215 (RING finger protein 215)
R58C (p.Arg58Cys) in RNF215 (RING finger protein 215) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
R58C (p.Arg58Cys) variant details
- p.Arg58Cys
- 1000Genomes rs1239529124
- TOPMed rs1239529124
- gnomAD rs1239529124
- Missense
- Variant Prioritization Score for Impact Estimate 0.338
- REVEL 0.20
- ESM-1b 0.00
- AlphaMissense 0.62
- CADD 24.80
- PolyPhen-2 0.34
- SIFT 0.01
- Population evidence available
- Structural context available