P3T (p.Pro3Thr) variant of RNF215 (RING finger protein 215)
P3T (p.Pro3Thr) in RNF215 (RING finger protein 215) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
P3T (p.Pro3Thr) variant details
- p.Pro3Thr
- TOPMed rs1459403959
- Missense
- Variant Prioritization Score for Impact Estimate 0.152
- REVEL 0.05
- ESM-1b 0.00
- AlphaMissense 0.09
- CADD 18.20
- PolyPhen-2 0.01
- SIFT 0.02
- Most common in the HGDP:TU population (allele frequency 0.1)
- Structural context available