P3L (p.Pro3Leu) variant of RNF215 (RING finger protein 215)
P3L (p.Pro3Leu) in RNF215 (RING finger protein 215) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
P3L (p.Pro3Leu) variant details
- p.Pro3Leu
- Ensembl rs1933618251
- Missense
- Variant Prioritization Score for Impact Estimate 0.228
- REVEL 0.07
- ESM-1b 0.00
- AlphaMissense 0.22
- CADD 22.40
- PolyPhen-2 0.01
- SIFT 0.01
- Most common in the Ashkenazi Jewish population (allele frequency 0.00058)
- Structural context available